2024年

• Qiuyu Han, Tomoyuki Koyama, Shugo Watabe, Shoichiro Ishizaki. Functional and structural properties of type V collagen from the skin of the shortbill spearfish (Tetrapturus angustirostris). Molecules. 29, 2518, 2024. https:// doi.org/10.3390/molecules29112518
• Kazuma Yoshizumi, Hitoshi Izumida, Haruka Hashimoto, Xinxin Liu, Tomoyuki Koyama. Determination of iodine contents in commercially kelp-containing foods using a simple colorimetric analysis method. Journal of Japanese Society of Shokuiku. 80, 57-64, 2024.【邦文：吉積一真，泉田仁，橋本晴賀，劉鑫鑫, 小山智之，簡易比色定量分析法による市販昆布加工食品中のヨウ素の定量.日本食育学会誌 57-64，2024（印刷中）】
• Wantanee Noichinda, Jie-Ting Geng, Hiroki Koyama, Tomoyuki Koyama, Kazufumi Osako. Effects of heat and argon treatment on lipid yield and quality of oil extracted from north pacific krill (Euphausia pacifica). Transactions of the Japan Society of Refrigerating and Air Conditioning Engineers. 42(2), 89-101, 2024.
• Xiaomei Yang, Yipeng Gua, Huazhong Liu, Feifei Shang, Tomoyuki Koyama. Modulation of the gut microbiota alleviates insulin resistance in type 2 diabetic mice by daucosterol from Eleocharis dulcis peel. Journal of Functional Foods. 114, 106092, 2024.
• Hisaaki Ito, Taro Honma, Hidetsugu Tabata, Tomoyuki Koyama, Shigeaki Ueno, Kayoko Kita, Toshihide Suzuki. Enzyme from Padina arborescens Holmes synthesizes parinaric acid, a conjugated tetraenoic fatty acid, from α -linolenic acid. J. Oleo Sci.. 73(5), 743-749, 2024.

2023年

• Kazuma Yoshizumi, Hitoshi Izumida, Haruka Hashimoto, Tomoyuki Koyama. Establishment of a simple quantitative analysis method for iodine in seaweed by colorimetric method. Algal Resources. 16, 85-89, 2023. (Abstract in English)
  【邦文：吉積一真，泉田仁，橋本晴賀，小山智之，比色法による海藻中ヨウ素の簡易定量分析法の確立. Algal Resources （日本応用藻類学会誌), 16, 85-89, 2023.】
• Jiyao Fei, Sohsuke Yamada, Takumi Satoh, Tomoyuki Koyama. Pharmacokinetic analysis of zonarol, a marine algal hydroquinone, in mice using HPLC with fluorescence detection. Antibiotics. 12(6), 1013, 2023. (https://doi.org/10.3390/antibiotics12061013)
• Xinxin Liu, Tomoyuki Koyama D-Pinitol Improved glucose metabolism and inhibited bone loss in mice with diabetic osteoporosis. Molecules. 28, 3870, 2023. (https://doi.org/10.3390/molecules28093870)
• Xinxin Liu, Chuan He, Tomoyuki Koyama D-pinitol ameliorated osteoporosis via elevating D-chiro inositol level in ovariectomized mice. J. Nutr. Sci. Vitaminol.. 69, 220-228, 2023.
• Jie Zhou, Qiuyu Han, Tomoyuki Koyama, Shoichiro Ishizaki. Preparation, purification and characterization of antibacterial and ACE inhibitory peptides from head protein hydrolysate of kuruma shrimp, Marsupenaeus japonicus. Molecules. 28, 894, 2023. (https://doi.org/10.3390/molecules28020894)
• Qiu-Yu Han, Tomoyuki Koyama, Shugo Watabe, Yuji Nagashima, Shoichiro Ishizaki. Isolation and characterization of collagen and collagen peptides with hyaluronidase inhibition activity derived from the skin of marlin (Istiophoridae). Molecules. 28, 889, 2023. (https://doi.org/10.3390/molecules28020889)

2022年

Parunya Thiyajai, Tomoyuki Koyama. Binary ethanol-water solvents affect betalain contents and healthpromoting properties of red Celosia argentea infloresence extracts. International Food Research Journal 29(1): 67-77, 2022.

2021年

Jia Han, Xin Guo, Tomoyuki Koyama, Daichi Kawai, Jing Zhang, Reimon Yamaguchi, Xiaolei Zhou, Yoshiharu Motoo, Takumi Satoh and Sohsuke Yamada. Zonarol Protected Liver from Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Fatty Liver Disease in a Mouse Model. Nutrients, 13, 3455, 2021. https://doi.org/10.3390/nu13103455

Yipeng Gu, Xiaomei Yang, Chaojie Shang, Truong Thi Phuong Thao, Tomoyuki Koyama. Inhibition and interactions of alpha-amylase by daucosterol from the peel of Chinese water chestnut (Eleocharis dulcis). Food & Function, 12, 8411-8424, 2021. (DOI: 10.1039/D1FO00887K)

Parunya Thiyajai, Daichi Kawai, Tomoyuki Koyama. Effective Purification Procedure of Amaranthin from Amaranthus Celosia argentea inflorescence. International Journal of Food Science and Agriculture 5(3), 370-375, 2021.

Lalitphan Kitsanayanyong, Jade Pahila, Yuki Ishikawa, Tomoyuki Koyama, Viswanath Kiron, Toshiaki Ohshima, Functional identification of ergothioneine transporter in rainbow trout (Oncorhynchus mykiss). Comparative Biochemistry and Physiology, Part B 256, 110631, 2021.

Yipeng Gu, Xiaomei Yang, Chaojie Shang, Truong Thi Phuong Thaoa Tomoyuki Koyama, Inhibitory properties of saponin from Eleocharis dulcis peel against a-glucosidase. Royal Society of Chemistry Advances, 11, 15400, 2021.

Chaojie Shang, Yipeng Gu, Tomoyuki Koyama, Major triterpenes, cycloeucalenone and 31-norcyclolaudenone as inhibitors against both α-glucosidase and α-amylase in banana peel. International Journal of Food Science and Technology 56, 3519-3526, 2021. (publ.: 22 Jan 2021, https://doi.org/10.1111/ijfs.14978).

2020-2016年

• Farhana Sharmin, Tomoyuki Koyama, Hiroki Koyama, Shoichiro Ishizaki, Cholesterol-binding ability of saponin from Japanese starfish. Journal of Food Science and Technology, 25, 2020. (DOI 10.1007/s13197-020-04809-4)
• Thao Thi Phuong Truong, Tomoyuki Koyama, Glucosinolate sinigrin improves insulin resistance to suppress glutathione consumption in type 2 diabetic mice. Journal of Diabetes & Metabolism, 11(10), No: 859, 2020.
• J. Pahila, H. Kaneda, R. Nagasaka, T. Koyama, T. Ohshima, Effects of ergothioneine-rich mushroom extracts on lipid oxidation and discoloration in salmon muscle stored at low temperatures, Food Chemistry, 233, 273-281, 2017.

2015-2011年

• S. Yamada, T. Koyama, H. Noguchi, Y. Ueda, R. Kitsuyama, H. Shimizu, A. Tanimoto, K. Wang, A. Nawata, T. Nakayama, Y. Sasaguri, T. Satoh, Marine Hydroquinone zonarol prevents inflammation and apoptosis in dextran sulfate sodium-induced mice ulcerative colitis, PLOS ONE, 10.1371/journal.pone.0113509, 2014.

• M. Shirosaki, T. Koyama, K. Yazawa. Suppressive effect of peach leaf extract on glucose absorption from the small intestine of mice. Biosci. Biotechnol. Biochem. 76(1), 89-94, 2012.

• K. Yazawa, K. Suga, A. Honma, M. Shirosaki, T. Koyama, Anti-inflammatory effects of seeds of the tropical fruit camu-camu (Myrciaria dubia). J. Nutr. Sci. Vitamino. 57(1), 104-107, 2011.
• A. Honma, T. Koyama, K. Yazawa, Anti-hyperglycemic effects of the Japanese red maple Acer pycnanthum and its constituents the ginnalins B and C. J. Enzyme Inhibit. Med. Chem. 26(2), 176-180, 2011.
• A. Ogawa, Y. Miyamae, A.i Honma, T. Koyama, K. Yazawa, H. Shigemori, Pycnalin, a new α-glucosidase inhibitor from Acer pycnanthum. Chem. Pharm. Bull. 59(5), 672-675, 2011.
• J. Wu, K. Fushimi, S. Tokuyama, M. Ohno, T. Miwa, T. Koyama, K. Yazawa, K. Nagai, T. Matsumoto, H. Hirai, H. Kawagishi, Functional-Food constituents in the fruiting bodies of Stropharia rugosoannulata. Biosci. Biotechnol. Biochem. 75(8), 1631-1634, 2011.
• J. Wu, J.H. Choi, M. Yoshida, H. Hirai, E. Harada, K. Masuda, T. Koyama, K. Yazawa, K. Noguchi, K. Nagasawa, H. Kawagishi, Osteoclast-forming suppressing compounds, gargalols A, B and C, from the edible mushroom Grifola gargal. Tetrahedron, 67(35), 6576-6581, 2011.

2010-2009年

• N. Maru, O. Ohno, T. Koyama, K. Yamada, D. Uemura, Papillamide, a novel fatty acid amide from the red alga Laurencia papillosa. Chem. Lett. 39, 366-367, 2010.
• M. Miyata, T. Koyama, K. Yazawa, Water extract of Houttuynia cordata Thunb. leaves exerts anti-obesity effects by inhibiting fatty acid and glycerol absorption. J. Nutr. Sci. Vitaminol. 56, 150-156, 2010.
• J.H. Choi, N. Abe, S. Kodani, K. Masuda, T. Koyama, K. Yazawa, M. Takahashi, H. Kawagishi, Osteoclast-forming suppressing compounds from the medicinal mushuroom Agrocybe chaxingu Huang (Agaricomycetideae). Int. J. Med. Mushrooms, 12, 151-155, 2010.
• K. Washida, M. Miyata, T. Koyama, K. Yazawa, K. Nomoto, Suppressive effect of Yamato-mana (Brassica rapa L. oleifera group) constituent 3-butenyl glucosinolate (gluconapin) on postprandial hypertriglyceridemia in mice. Biosci. Biotech. Biochem. 74, 1286-1289, 2010.
• K. Masuda, T. Kawaguchi, T. Koyama, T. Nishimura, H. Kawagishi, K. Yazawa, Osteoclast-forming suppressive compounds from Anoectochilus formosanus. Japanese Jap. J. complement. altern. med. 7, 121-124, 2010.
• A. Honma, T. Koyama, K. Yazawa, Anti-hyperglycemic effects of sugar maple Acer saccharum and its constituent acertannin, Food Chem. 123, 390–394, 2010.
• N. Maru, T. Koyama, O. Ohno, K. Yamada, D. Uemura, Sunabedine, a novel toxic bromotyrosine-derivative alkaloid from Okinawan sponge, order Verongida. Heterocycles, 82, 371-375, 2010.
• A. Honma, T. Koyama, K. Yazawa, Anti-hyperglycemic effects of Japanese maple Acer amoenum leaf extract and its constituent corilagin. J. Wood Sci. 56, 507-512, 2010.

• J.H. Choi, A. Ogawa, N. Abe, K. Masuda, T. Koyama, K. Yazawa, H. Kawagishi, Chaxines B, C, D, and E from the edible mushroom Agrocybe chaxingu. Tetrahedron, 65, 9850–9853, 2009.
• M. Ikeuchi, T. Koyama, S. Takei, T. Kino, K. Yazawa, Effects of benzylglucosinolate on endurance capacity in mice, J. Health Sci. 55, 178-182, 2009.
• K. Akamine, T. Koyama, K. Yazawa, Banana peel extract suppresses prostate gland enlargement in testosterone-treated mice, Biosci. Biotech. Biochem. 73, 1911-1914, 2009.
• M. Miyata, T. Koyama, T. Kamitani, T. Toda, K. Yazawa, Anti-obesity effect on rodents of the traditional Japanese food, Tororo-kombu, shaved Laminaria. Biosci. Biotech. Biochem. 73, 2326-2328, 2009.

2008-2006年

• M. Shirosaki, T. Koyama, K. Yazawa, Anti-hyperglycemic activity of kiwifruit leaf (Actinidia deliciosa) in mice. Biosci. Biotechnol. Biochem. 72, 1099-1102, 2008.
• M. Nishihara, M. Kamata, T. Koyama, K. Yazawa, New phospholipase A1-producing bacteria from a marine fish. Mar. Biotechnol. 10, 382-387, 2008.
• O. Ohno, M. Ye, T. Koyama, K. Yazawa, E. Mura, H. Matsumoto, T. Ichino, K. Yamada, K. Nakamura, T. Ohno, K. Yamaguchi, J. Ishida, A. Fukamizdu, D. Uemura, Inhibitory effects of benzyl benzoate and its derivatives on angiotensin II-induced hypertension. Bioorg. Med. Chem. 16, 7843-7852, 2008.

• M. Kitamura, T. Koyama, Y. Nakano, D. Uemura, Characterization of a natural inducer of coral larval metamorphosis. J. Exp. Mar. Biol. Ecol. 340, 96-102, 2007.
• M. Ikeuchi, T. Koyama, J. Takahashi, K. Yazawa, Effects of astaxanthin in obese mice fed a high-fat diet. Biosci. Biotechnol. Biochem. 71, 893-899, 2007.
• M. Kita, M.C. Roy, E.R.O. Siwu, I. Noma, T. Takiguchi, M. Itoh, K. Yamada, T. Koyama, T. Iwashita, D. Uemura, Durinskiol A, a long carbon-chain polyol compound from the symbiotic dinoflagellate Durinskia sp. Tetrahedron Lett. 48, 3423-3427,2007.
• M. Kita, M.C. Roy, E.R.O. Siwu, I. Noma, T. Takiguchi, K. Yamada, T. Koyama, T. Iwashita, A. Wakamiya, D. Uemura, Relative stereochemistries of the ether rings and sugar moieties in Durinskiol A. Tetrahedron Lett. 48, 3429-3432, 2007.
• M. Kita, N. Ohishi, K. Konishi, M. Kondo, T. Koyama, M. Kitamura, K. Yamada, D. Uemura, Symbiodinolide, a novel polyol macrolide that activates N-type Ca2+ channel from the symbiotic dinoflagellate Symbiodinium sp. Tetrahedron, 63, 6241-6251, 2007.

• T. Koyama, R. Chounan, D. Uemura, K. Yamaguchi, K. Yazawa, Hepatoprotective effect of a hot-water extract from the edible thorny oyster Spondylus varius on carbon tetrachloride-induced liver injury in mice. Biosci. Biotechnol. Biochem. 70, 729-731, 2006.
• M. Ikeuchi, K. Yamaguchi, T. Koyama, Y. Sono, K. Yazawa, Effects of fenugreek seeds (Trigonella foenum greaecum) extract on endurance capacity in mice. J. Nutr. Sci. Vitaminol. 52, 287-292, 2006.
• M. Ikeuchi, T. Koyama, J. Takahashi, K. Yazawa, Effects of astaxanthin supplementation on exercise-induced fatigue in mice. Biol. Pharm. Bull. 29, 2106-2110, 2006.

before 2005

• Y. Aniya, T. Koyama, C. Miyagi, M. Miyahira, C. Inomata, S. Kinoshita, T. Ichiba, Free radical scavenging and hepatoprotective actions of the medicinal herb, Crassocephalum crepidioides from the Okinawa Islands. Biol. Pharm. Bull. 28, 19-23, 2005.
• K. Noguchi, M. Sakanashi, T. Matsuzaki, J. Nakasone, M. Sakanashi, T. Koyama, N. Hamadate, M. Sakanashi, Cardiovascular effects and lethality of venom from nematosysts of the box-jellyfish Chiropsalmus quadrigatus (Habu-kurage) in anaesthetized rats. Toxicon, 45, 519-526, 2005.
• M. Kita, N. Ohishi, K. Washida, M. Kondo, K. Yamada, T. Koyama, D. Uemura, Symbioimine and neosymbioimine, amphoteric iminium metabolites from the symbiotic marine dinoflagellate Symbiodinium sp. Bioorg. Med. Chem. 13, 5253-5258, 2005.
• M. Kitamura, T. Koyama, Y. Nakano, D. Uemura, Corallinafuran and corallinaether, novel toxic compounds from crustose coralline red algae. Chem. Lett. 34, 1272-1273, 2005.
• M. Kita, M. Kitamura, T. Koyama, T. Teruya, H. Matsumoto, Y. Nakano, D. Uemura, Feeding attractants for the muricid gastropod Drupella cornus, a coral predator. Tetrahedron Lett. 46, 8583-8585, 2005.

• T. Teruya, S. Nakagawa, T. Koyama, H. Arimoto, M. Kita, D. Uemura, Nakiterpiosin and nakiterpiosinone, novel cytotoxic C-nor-D-homosteroid from the Okinawan Sponge Terpios hoshinota. Tetrahedron, 60, 6989-6993, 2004.
• M. Kita, M. Kondo, T. Koyama, K. Yamada, T. Matsumoto, K.H. Lee, J.T. Woo, D. Uemura, Symbioimine exhibiting inhibitory effect of osteoclast differentiation, from the symbiotic marine dinoflagellate Symbiodinium sp. J. Am. Chem. Soc. 126(15), 4794-4795, 2004.